Washington: The US Senate, fending off opposition from some conservative Republicans, voted on Wednesday to spend $48 billion (Dh176 billion) to fight Aids worldwide over the next five years.

By a vote of 80-16, the Senate passed the legislation and ended weeks of delays orchestrated by some Republicans who thought the measure spent too much and objected to other provisions.

"In 2003, President [George] Bush and this Congress launched the largest public health programme in the history of the world," said Senate Foreign Relations Committee Chairman Joseph Biden, a Delaware Democrat, who pushed the legislation. "It is saving lives, millions of them."

The House of Representatives passed its version of the Bill on April 2. The House and Senate will have to work out their differences to craft a final version. "With passage of today's Bill we are one step closer to ensuring that this excellent program continues to help those in need. I encourage the full Congress to move quickly to send me final legislation that I can sign," President George W. Bush said in a statement.

Bush had requested $30 billion over five years but has indicated he would go along with the higher spending.

Backers of the legislation hope it will encourage other wealthy countries to boost their global Aids funding. Twelve African nations, which have been suffering from a rapid spread of the human immunodeficiency virus (HIV) that causes Aids, would benefit most from the added US money.